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J. Phys. IV France
Volume 11, Numéro PR10, Décembre 2001
Journées d'Étude des Équilibres entre Phases
Page(s) Pr10-261 - Pr10-263
Journées d'Étude des Équilibres entre Phases

J. Phys. IV France 11 (2001) Pr10-261-Pr10-263

DOI: 10.1051/jp4:20011042

Physicochemical study of a synthetic peptide belonging to human filaggrin protein

T. Pérez1, M. Muñoz2, Y. Jaouher2, M.A. Alsina2 and I. Haro1

1  Department of Peptide & Protein Chemistry, IIQAB-CSIC, Jordi Girona 18-26, 08034 Barcelona, Spain
2  Department of Physicochemistry, Faculty of Pharmacy, University of Barcelona, Av. Joan XXIII, s/n, 08028 Barcelona, Spain

In the present work the physicochemical characterization of the (306-324) synthetic peptide sequence from human filaggrin protein and its palmitoilated derivative was carried out. Monomolecular layers of dipalmitoilphosphatidilcholine (DPPC) were used to study lipid/peptide interactions. Measurements of surface activity, compression isotherms and DPPC miscibility are reported.

© EDP Sciences 2001