J. Phys. IV France 11 (2001) Pr10-261-Pr10-263
Physicochemical study of a synthetic peptide belonging to human filaggrin proteinT. Pérez1, M. Muñoz2, Y. Jaouher2, M.A. Alsina2 and I. Haro1
1 Department of Peptide & Protein Chemistry, IIQAB-CSIC, Jordi Girona 18-26, 08034 Barcelona, Spain
2 Department of Physicochemistry, Faculty of Pharmacy, University of Barcelona, Av. Joan XXIII, s/n, 08028 Barcelona, Spain
In the present work the physicochemical characterization of the (306-324) synthetic peptide sequence from human filaggrin protein and its palmitoilated derivative was carried out. Monomolecular layers of dipalmitoilphosphatidilcholine (DPPC) were used to study lipid/peptide interactions. Measurements of surface activity, compression isotherms and DPPC miscibility are reported.
© EDP Sciences 2001