| Numéro |
J. Phys. IV France
Volume 04, Numéro C7, Juillet 1994
8th International Topical Meeting on Photoacoustic and Photothermal Phenomena8 ITMP3 / 8éme conférence internationale de photoacoustique et photothermique |
|
|---|---|---|
| Page(s) | C7-449 - C7-451 | |
| DOI | https://doi.org/10.1051/jp4:19947104 | |
8th International Topical Meeting on Photoacoustic and Photothermal Phenomena
8 ITMP3 / 8éme conférence internationale de photoacoustique et photothermique
J. Phys. IV France 04 (1994) C7-449-C7-451
DOI: 10.1051/jp4:19947104
1 DIAS, UMIST, M60 1QD, Manchester, U.K.
2 Unilever Research, Port Sunlight Laboratory, L63 3JW, Bebington, U.K.
© EDP Sciences 1994
8 ITMP3 / 8éme conférence internationale de photoacoustique et photothermique
J. Phys. IV France 04 (1994) C7-449-C7-451
DOI: 10.1051/jp4:19947104
Fourier transform infrared photoacoustic spectroscopy to study the penetration of substances through skin
M.L. Baesso1, R.D. Snook1 and J.J. Andrew21 DIAS, UMIST, M60 1QD, Manchester, U.K.
2 Unilever Research, Port Sunlight Laboratory, L63 3JW, Bebington, U.K.
Abstract
Step-scan Fourier Transform Inflared (FT-IR) Photoacoustic Spectroscopy (PAS) has been used to study the penetration of substances through abdominal pig skin. The experiments were performed in vitro and dimethylsulfoxide (DMSO) was applied either onto the surface or the bottom of the sample. The results demonstrated that DMSO propagated fast through the skin from the bottom surface. The ease of identification of this substance in this spectral range showed the potential of the technique, suggesting that penetration and distribution of other chemicals through the skin can be investigated by FT-IR PAS.
© EDP Sciences 1994