EDP Sciences Journals List
Issue J. Phys. IV France
Volume 04, Number C4, Avril 1994
3rd International Conference Laser M2P
Page(s) C4-270 - C4-270
DOI http://dx.doi.org/10.1051/jp4:1994463

3rd International Conference Laser M2P

J. Phys. IV France 04 (1994) C4-270-C4-270

DOI: 10.1051/jp4:1994463

Safety with laser during retinal therapy : an electroretinographic study

E.M. EL-SAYED1, M.S. TALAAT1 and A.M. SALLAM2

1  Physics Department, Faculty of Science, Ain Shams University, Cairo, Egypt
2  Physics Department, Faculty of Science, Zagazig University, Benha, Egypt


Abstract
Studies of the retinal sensitivity, as reflected in the ERG records, have been made, before, during, and after exposure of the eye to an argon laser beam ( > = 488 nm ; intensity 1 mW/cm2 ; durations 0.12 and 0.25 sec). The applied retinal load thus was similar as that during retinal treatments. The ERG records were carried out at different temperatures (10 - 30°C) for both light and dark adapted eyes. The aim of this study was to assess the best suitable conditions for retinal laser treatments without affecting other retinal tissues. The obtained results showed that the argon laser therapy causes some damage to the eye which is paralleled by a noticeable change in the b-wave amplitude (Ab) of the electroretinogram. This damage recovers faster when the laser dose and the eye temperature are reduced. Also it was preferable to perform these treatments in dark adapted eyes rather than in light adapted eyes. Simple calculations of the changes in the external K+ concentration, ΔK, induced by light stimulation were performed, before and after laser treatment, using Nernst equation modified by Miller relating Ab to the logarithm of the external K+ concentration. This led to the conclusion that laser treatment has an indirect effect on the eye through its direct effects on the pigment epithelium and photoreceptor membrane permeabilities to K+. Moreover, calculations of the repair-damage ratio represented by Ab variations, after laser exposure, helped for optimizing the laser conditions during treatments. This indicated that the ERG is a sensitive tool for studying the effects on the eye during treatments.



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