J. Phys. IV France 122 (2004) 211-215
Interaction study of three overlapping synthetic peptides belonging to E2 protein of GBV-C/HGV with liposomes as biomembrane modelsN. Rojo1, M. Muñoz2, M. Pujol2, M.A. Alsina2 and I. Haro1
1 Department of Peptide & Protein Chemistry. Institute for Chemical and Environmental Research (IIQAB-CSIC), Jordi Girona 18-26, 08034 Barcelona, Spain
2 Unidad Asociada CSIC: "Péptidos y Proteínas: Estudios fisicoquímicos", Department of Physicochemistry, Faculty of Pharmacy, University of Barcelona, Av. Joan XXIII s/n, 08028 Barcelona, Spain
In this work we studied by DSC the interaction of three antigenic overlapping peptides belonging to the E2 envelope protein of Hepatitis G virus, namely E2(39-53), E2(32-53) and E2(26-53), with liposomes of different lipid composition (DPPC, DMPC and DMPG) as biomembrane models. The effect of the three selected peptides on the thermotropic behaviour of lipid bilayers has been evaluated.
© EDP Sciences 2004