J. Phys. IV France 03 (1993) C8-221-C8-227
Small angle X-ray and neutron scattering from ganglioside micellar solutionsL. CANTÙ1, M. CORTI2, T. ZEMB3 and C. WILLIAMS4
1 Department of Chemistry and Biochemistry, University of Milan, via Saldini 50, 20133 Milano, Italy
2 Department of Electronics, University of Pavia, via Abbiategrasso 209, 27100 Pavia, Italy
3 C.E.A SCM, Bat. 125, C.E. Saclay, 91191 Gif-sur-Yvette cedex, France
4 L.U.R.E., Bat. 109, Centre Universitaire Paris-Sud, 91405 Orsay cedex, France
The ganglioside GM1 is a biological amphiphile with a double tail hydrophobic part and an oligosaccharide chain headgroup. In solution it forms micelles which interact by electrostatic repulsion. The micellar parameters obtained at low concentration by light and neutron scattering are used to interpret the small angle X-ray experiments performed at high concentration. The combination of the contrast inhomogeneity inside the micelle with the sharp structure-factor peaks, due to the strong electrostatic interaction, makes X-ray scattering spectra very sensitive to small changes in the micellar parameters.
© EDP Sciences 1993